Dr Helen Connaris

Senior Research Fellow in Enzyme Production, Purification and Assessment (Translationally Focused)

Researcher profile

Phone

+44 (0)1334 46 3698

Email

hc6@st-andrews.ac.uk

 

Selected publications

• Open access

  The impact of viral infection on the chemistries of the Earth’s most abundant photosynthesisers: metabolically talented aquatic cyanobacteria

  Wang, Y., Ferrinho, S., Connaris, H. & Goss, R., 4 Aug 2023, In: Biomolecules. 13, 8, 29 p., 1218.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Halogenases: a palette of emerging opportunities for synthetic biology–synthetic chemistry and C–H functionalisation

  Crowe, C., Molyneux, S., Sharma, S. V., Zhang, Y., Gkotsi, D. S., Connaris, H. & Goss, R. J. M., 7 Sept 2021, In: Chemical Society Reviews. 17, 50, p. 9443-9481 39 p.

  Research output: Contribution to journal › Review article › peer-review

• Immunomodulatory Compounds

  Taylor, G. L. & Connaris, H., 30 Jul 2015, IPC No. A61K31/74, Patent No. WO2015110831 (A1)

  Research output: Patent

• Open access

  Sialic acid-binding protein Sp2CBMTD protects mice against lethal challenge with emerging influenza A (H7N9) virus

  Govorkova, E. A., Baranovich, T., Marathe, B. M., Yang, L., Taylor, M. A., Webster, R. G., Taylor, G. L. & Connaris, H., Mar 2015, In: Antimicrobial Agents and Chemotherapy. 59, 3, p. 1495-1504 10 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor

  Yang, L., Connaris, H., Potter, J. A. & Taylor, G. L., 20 Aug 2015, In: BMC Structural Biology. 15, 10 p., 15.

  Research output: Contribution to journal › Article › peer-review

• Prevention of influenza by targeting host receptors using engineered proteins

  Connaris, H., Govorkova, E. A., Ligertwood, Y., Dutia, B. M., Yang, L., Tauber, S., Taylor, M. A., Alias, N., Hagan, R., Nash, A. A., Webster, R. G. & Taylor, G. L., 29 Apr 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 17, p. 6401-6406

  Research output: Contribution to journal › Article › peer-review

• Carbohydrate Binding Molecules

  Connaris, H. & Taylor, G. L., 3 Nov 2011, IPC No. A61P31/04, Patent No. US2011269670 (A1)

  Research output: Patent

• Enhancing the receptor affinity of the sialic acid-binding domain of Vibrio cholerae sialidase through multivalency

  Connaris, H., Crocker, PR. & Taylor, G. L., 13 Mar 2009, In: Journal of Biological Chemistry. 284, p. 7339-7351 13 p.

  Research output: Contribution to journal › Article › peer-review

• Sialic acid recognition by Vibrio cholerae neuraminidase

  Moustafa, I., Connaris, H., Taylor, M., Zaitsev, V., Wilson, JC., Kiefel, MJ., von Itzstein, M. & Taylor, G. L., 24 Sept 2004, In: Journal of Biological Chemistry. 279, 39, p. 40819-40826 8 p.

  Research output: Contribution to journal › Article › peer-review

• The Structural Basis for Substrate Promiscuity in 2-Keto-3-deoxygluconate aldolase from the Entner-Doudoroff Pathway in Sulfolobus solfataricus

  Theodossis, A., Walden, H., Westwick, EJ., Connaris, H., Lamble, HJ., Hough, DW., Danson, MJ. & Taylor, G. L., 15 Oct 2004, In: Journal of Biological Chemistry. 279, 42, p. 43886-43892 7 p.

  Research output: Contribution to journal › Article › peer-review

 

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